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sh!+_stains · Joined: 07 Feb 2008 Posts: 40

Districts with highest rates of TB in cattle have lowest rates of TB death in humans:

What Dr. Hermon-Taylor was talking about in the BBC video and how why farmers and vets may acquire a natural immunity to MAP in its classic form.

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billyfish · Joined: 07 Jan 2008 Posts: 27

Human TB that kills is Mycobacterium Tuberculosis I think. Cow TB is Mycobacterium Bovis. I understand that any TB protects against the rest so maybe thats the explanation.

Here in the UK we all used to have a BCG vaccination for TB at around age 14, it protected against M Bovis. They have stopped this now.

billyfish · Joined: 07 Jan 2008 Posts: 27

Sorry there's more, I understand that all vets and dairy farmers here are vaccinated against Bovine TB, if they are not reactors to the tuberculin test. Reactors include those with avian tb, that might protect against MAP in the farming community, its fairly certain that farmers and vets are more likely to get a dose of a bug that protects them against MAP.

Its a similar situation to smallpox, where people who milked cows got cowpox, that made them immune, read the history books please.

billyfish · Joined: 07 Jan 2008 Posts: 27

Just looked up smallpox, cowpox, had a thought. Maybe when we all started on this healthy pasteurised milk. It stopped us getting an infection that protected us from MAP, perhaps the farmers still get it. The most likely candidate for this is Mycobacterium Avium. (not paratuberculosis) this one is easily killed.

Maybe improved pasteurisation is making things worse for some people?

david.crichton · Joined: 02 May 2008 Posts: 27

Makes sense to me billyfish: active immunity; Edward Jenner; 1796; milkmaids; prick a young boy with a needle that touched a milkmaids cowpox sore; voila, cowpox vaccine preventing smallpox...

Check out this article. Could the early and regular contact with farm animals, "especially cattle" infected with less virulent forms of MAP or other mycobacteria be the reason for the observed inverse relationship between contact with farm animals early in life and juvenile CD and UC?