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Inform Canadians of the evidence linking Crohn's disease to Mycobacterium Avium Paratuberculosis and Johne's disease in animals
 
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Here is a very interesting idea

 
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Exploited



Joined: 24 Jan 2008
Posts: 41

PostPosted: Wed May 07, 2008 2:54 am    Post subject: Here is a very interesting idea Reply with quote

http://michellerainey.com/
http://www.toronto420.com/crohns/index.html

Apparently medicinal cannabis is quite helpful for people with Crohn's.
She is legally entitled to grow and use it, if you have Crohn's you are qualified for Canada's medical marijuana program.

Its not to be smoked, but rather ingested where is apparently is quite a powerful anti-inflammatory and increases apatite.

I'm right near Toronto, I think I might have to suddenly take a turn for the worst Smile
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david.crichton



Joined: 02 May 2008
Posts: 27

PostPosted: Wed May 07, 2008 11:04 pm    Post subject: Reply with quote

Would you still want to take a turn for the worse in order to take cannabis if it wouldn't get you high?

Maybe more research into the below could be helpful:
http://www.ncbi.nlm.nih.gov/pubme...bmed_ResultsPanel.Pubmed_RVDocSum

The endocannabinoid system in the physiology and pathophysiology of the gastrointestinal tract.
Massa F, Storr M, Lutz B.

Department of Physiological Chemistry, Johannes Gutenberg-University Mainz, Duesbergweg 6, 55099 Mainz, Germany.

Numerous investigations have recently demonstrated the important roles of the endocannabinoid system in the gastrointestinal (GI) tract under physiological and pathophysiological conditions. In the GI tract, cannabinoid type 1 (CB1) receptors are present in neurons of the enteric nervous system and in sensory terminals of vagal and spinal neurons, while cannabinoid type 2 receptors are located in immune cells. Activation of CB1 receptors was shown to modulate several functions in the GI tract, including gastric secretion, gastric emptying and intestinal motility. Under pathophysiological conditions induced experimentally in rodents, the endocannabinoid system conveys protection to the GI tract (e.g. from inflammation and abnormally high gastric and enteric secretions). Such protective activities are largely in agreement with anecdotal reports from folk medicine on the use of Cannabis sativa extracts by subjects suffering from various GI disorders. Thus, the endocannabinoid system may serve as a potentially promising therapeutic target against different GI disorders, including frankly inflammatory bowel diseases (e.g. Crohn's disease), functional bowel diseases (e.g. irritable bowel syndrome) and secretion- and motility-related disorders. As stimulation of this modulatory system by CB1 receptor agonists can lead to unwanted psychotropic side effects, an alternative and promising avenue for therapeutic applications resides in the treatment with CB1 receptor agonists that are unable to cross the blood-brain barrier, or with compounds that inhibit the degradation of endogenous ligands (endocannabinoids) of CB1 receptors, hence prolonging the activity of the endocannabinoid system.
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